Cigarette smoke-induced emphysema in A/J mice is associated with pulmonary oxidative stress, apoptosis of lung cells, and global alterations in gene expression
Am J Physiol Lung Cell Mol Physiol Rangasamy et al.
296: L888
Supplemental Figures and Tables
6 tables in PDF and Excel format; 2 figures in PDF format; plus additional material in PDF.
Files in this Data Supplement:
Table S3 -
(PDF) The commonly up-regulated genes in lungs of A/J mice exposed to CS for different time periods.
Table S4 -
(PDF) Number of up-regulated and down-regulated genes (in parenthesis) belonging to each functional category.
Table S6 -
(PDF) Some of the down-regulated genes in the lungs from CS exposed A/J mice whose deletion or overexpression have been shown to contribute to the pathogenesis of emphysema in various mice models.
Table S1
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(Excel) Differential expression of gene clusters in the lungs of air vs cigarette smoke exposed A/J mice.
Table S2
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(Excel) Down-regulated genes in the lungs of A/J mice exposed to cigarette smoke for various time periods.
Table S5
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(Excel) A comparison of the overlap of differentially expressed genes in the lungs of A/J mice with the lungs of CS exposed rat and 2 human COPD gene expression studies.