There have been many efforts to develop good animal models of bronchopulmonary dysplasia (BPD) in order to better understand the pathophysiology and mechanisms underlying development of BPD as well as to test potential strategies for its prevention and treatment. This perspective summarizes the features of common animal models of BPD and the strengths and limitations of such models. Potential optimal approaches to development of animal models are indicated, with the underlying concepts that require emphasis.
- animal model
- bronchopulmonary dysplasia
- infant, premature
- neonatal respiratory distress syndrome
- chronic lung injury
- Copyright © 2016, American Journal of Physiology-Lung Cellular and Molecular Physiology