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Contents: Volume 276, Issue 2
February 1999 [Index by Author]
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Cover: Spheroids derived as tissue explants from human airway epithelium, formed by 1 layer of polarized epithelial cells, with apical, ciliated membrane facing outward and basolateral membrane facing the fluid-filled lumen. Spheroids are inflated because of an inward ion transport followed by water. Top: experimental setup for transepithelial potential difference measurement, with holding pipette (left) and approaching micropipette (right). Focus is at periphery of the spheroid (~275-µm diam; Nikon Coolpix 900 and Diaphot 300). Bottom: broken spheroid illustrates epithelial monolayer and empty lumen (~225-µm diam; scanning electron microscopy). From P. S. Pedersen, O. Frederiksen, N.-H. Holstein-Rathlou, P. L. Larsen, and K. Qvortrup. Ion transport in epithelial spheroids derived from human airway cells. Am. J. Physiol. 276 (Lung Cell. Mol. Physiol. 20): L75-L80, 1999.
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