TRANSLATIONAL PHYSIOLOGY:

Janet L. Rossi, Anastasia V. Velentza, David M. Steinhorn, D. Martin Watterson, and Mark S. Wainwright

MLCK210 gene knockout or kinase inhibition preserves lung function following endotoxin-induced lung injury in mice
Am J Physiol Lung Cell Mol Physiol 292: L1327-L1334, 2007. First published February 16, 2007; doi:10.1152/ajplung.00380.2006 [Abstract] [Full Text] [PDF]  

ARTICLES:

Ahmed Nadeem, Ming Fan, Habib R. Ansari, Catherine Ledent, and S. Jamal Mustafa

Enhanced airway reactivity and inflammation in A_2A adenosine receptor-deficient allergic mice
Am J Physiol Lung Cell Mol Physiol 292: L1335-L1344, 2007. First published February 9, 2007; doi:10.1152/ajplung.00416.2006 [Abstract] [Full Text] [PDF]  

Theresa R. Grover, Tiina M. Asikainen, John P. Kinsella, Steven H. Abman, and Carl W. White

Hypoxia-inducible factors HIF-1 and HIF-2 are decreased in an experimental model of severe respiratory distress syndrome in preterm lambs
Am J Physiol Lung Cell Mol Physiol 292: L1345-L1351, 2007. First published February 16, 2007; doi:10.1152/ajplung.00372.2006 [Abstract] [Full Text] [PDF]  

Mike M. Myerburg, Joseph D. Latoche, Erin E. McKenna, Laura P. Stabile, Jill S. Siegfried, Carol A. Feghali-Bostwick, and Joseph M. Pilewski

Hepatocyte growth factor and other fibroblast secretions modulate the phenotype of human bronchial epithelial cells
Am J Physiol Lung Cell Mol Physiol 292: L1352-L1360, 2007. First published February 16, 2007; doi:10.1152/ajplung.00328.2006 [Abstract] [Full Text] [PDF]  

Christy A. Barlow, Trisha F. Barrett, Arti Shukla, Brooke T. Mossman, and Karen M. Lounsbury

Asbestos-mediated CREB phosphorylation is regulated by protein kinase A and extracellular signal-regulated kinases 1/2
Am J Physiol Lung Cell Mol Physiol 292: L1361-L1369, 2007. First published February 23, 2007; doi:10.1152/ajplung.00279.2006 [Abstract] [Full Text] [PDF]  

Richard D. Bland, Liwen Xu, Robert Ertsey, Marlene Rabinovitch, Kurt H. Albertine, Karen A. Wynn, Vasanth H. Kumar, Rita M. Ryan, Daniel D. Swartz, Katalin Csiszar, and Keith S. K. Fong

Dysregulation of pulmonary elastin synthesis and assembly in preterm lambs with chronic lung disease
Am J Physiol Lung Cell Mol Physiol 292: L1370-L1384, 2007. First published February 9, 2007; doi:10.1152/ajplung.00367.2006 [Abstract] [Full Text] [PDF] [Supplemental Figures]  

K. G. Tirumurugaan, J. A. Jude, B. N. Kang, R. A. Panettieri, T. F. Walseth, and M. S. Kannan

TNF- induced CD38 expression in human airway smooth muscle cells: role of MAP kinases and transcription factors NF-B and AP-1
Am J Physiol Lung Cell Mol Physiol 292: L1385-L1395, 2007. First published February 23, 2007; doi:10.1152/ajplung.00472.2006 [Abstract] [Full Text] [PDF]  

Karine Rousseau, Sara Kirkham, Shaun McKane, Richard Newton, Peter Clegg, and David J. Thornton

Muc5b and Muc5ac are the major oligomeric mucins in equine airway mucus
Am J Physiol Lung Cell Mol Physiol 292: L1396-L1404, 2007. First published February 9, 2007; doi:10.1152/ajplung.00444.2006 [Abstract] [Full Text] [PDF]  

Bart G. J. Dekkers, Dedmer Schaafsma, S. Adriaan Nelemans, Johan Zaagsma, and Herman Meurs

Extracellular matrix proteins differentially regulate airway smooth muscle phenotype and function
Am J Physiol Lung Cell Mol Physiol 292: L1405-L1413, 2007. First published February 9, 2007; doi:10.1152/ajplung.00331.2006 [Abstract] [Full Text] [PDF]  

Yoko Osawa, Peter D. Yim, Dingbang Xu, Reynold A. Panettieri, and Charles W. Emala

Raf-1 kinase mediates adenylyl cyclase sensitization by TNF- in human airway smooth muscle cells
Am J Physiol Lung Cell Mol Physiol 292: L1414-L1421, 2007. First published February 2, 2007; doi:10.1152/ajplung.00123.2006 [Abstract] [Full Text] [PDF]  

Maud Pierre, Marie-Odile Husson, Rozenn Le Berre, Jean-Luc Desseyn, Claude Galabert, Laurent Béghin, Christopher Beermann, André Dagenais, Yves Berthiaume, Bruno Cardinaud, Pascal Barbry, Frédéric Gottrand, and Benoît P. Guery

Omega-3 polyunsaturated fatty acids improve host response in chronic Pseudomonas aeruginosa lung infection in mice
Am J Physiol Lung Cell Mol Physiol 292: L1422-L1431, 2007. First published February 23, 2007; doi:10.1152/ajplung.00337.2006 [Abstract] [Full Text] [PDF]  

Horst Fischer, Beate Illek, Walter E. Finkbeiner, and Jonathan H. Widdicombe

Basolateral Cl channels in primary airway epithelial cultures
Am J Physiol Lung Cell Mol Physiol 292: L1432-L1443, 2007. First published February 23, 2007; doi:10.1152/ajplung.00032.2007 [Abstract] [Full Text] [PDF]  

David M. Brown, Laura Hutchison, Kenneth Donaldson, and Vicki Stone

The effects of PM₁₀ particles and oxidative stress on macrophages and lung epithelial cells: modulating effects of calcium-signaling antagonists
Am J Physiol Lung Cell Mol Physiol 292: L1444-L1451, 2007. First published March 16, 2007; doi:10.1152/ajplung.00162.2006 [Abstract] [Full Text] [PDF]  

Randal O. Dull, Ian Mecham, and Scott McJames

Heparan sulfates mediate pressure-induced increase in lung endothelial hydraulic conductivity via nitric oxide/reactive oxygen species
Am J Physiol Lung Cell Mol Physiol 292: L1452-L1458, 2007. First published March 9, 2007; doi:10.1152/ajplung.00376.2006 [Abstract] [Full Text] [PDF]  

Weilin Zhou, Chiranjib Dasgupta, Sewite Negash, and J. Usha Raj

Modulation of pulmonary vascular smooth muscle cell phenotype in hypoxia: role of cGMP-dependent protein kinase
Am J Physiol Lung Cell Mol Physiol 292: L1459-L1466, 2007. First published February 23, 2007; doi:10.1152/ajplung.00143.2006 [Abstract] [Full Text] [PDF]  

Liping Tang, Bao Luo, Rakesh P. Patel, Yiqun Ling, Junlan Zhang, and Michael B. Fallon

Modulation of pulmonary endothelial endothelin B receptor expression and signaling: implications for experimental hepatopulmonary syndrome
Am J Physiol Lung Cell Mol Physiol 292: L1467-L1472, 2007. First published March 2, 2007; doi:10.1152/ajplung.00446.2006 [Abstract] [Full Text] [PDF]  

Moira Hagen, Karen Fagan, Wolfgang Steudel, Michelle Carr, Kirk Lane, David M. Rodman, and James West

Interaction of interleukin-6 and the BMP pathway in pulmonary smooth muscle
Am J Physiol Lung Cell Mol Physiol 292: L1473-L1479, 2007. First published February 23, 2007; doi:10.1152/ajplung.00197.2006 [Abstract] [Full Text] [PDF]  

Akihito Sasaki, Shouzaburoh Doi, Shuki Mizutani, and Hiroshi Azuma

Roles of accumulated endogenous nitric oxide synthase inhibitors, enhanced arginase activity, and attenuated nitric oxide synthase activity in endothelial cells for pulmonary hypertension in rats
Am J Physiol Lung Cell Mol Physiol 292: L1480-L1487, 2007. First published February 23, 2007; doi:10.1152/ajplung.00360.2006 [Abstract] [Full Text] [PDF]  

Ramasamy Jagadeeswaran, Sujatha Jagadeeswaran, Vytas P. Bindokas, and Ravi Salgia

Activation of HGF/c-Met pathway contributes to the reactive oxygen species generation and motility of small cell lung cancer cells
Am J Physiol Lung Cell Mol Physiol 292: L1488-L1494, 2007. First published February 23, 2007; doi:10.1152/ajplung.00147.2006 [Abstract] [Full Text] [PDF]  

Jing Wang, Francis Gigliotti, Samir P. Bhagwat, Sanjay B. Maggirwar, and Terry W. Wright

Pneumocystis stimulates MCP-1 production by alveolar epithelial cells through a JNK-dependent mechanism
Am J Physiol Lung Cell Mol Physiol 292: L1495-L1505, 2007. First published February 16, 2007; doi:10.1152/ajplung.00452.2006 [Abstract] [Full Text] [PDF]  

Horst Fischer, Linda K. Gonzales, Venkatadri Kolla, Christian Schwarzer, Françoise Miot, Beate Illek, and Philip L. Ballard

Developmental regulation of DUOX1 expression and function in human fetal lung epithelial cells
Am J Physiol Lung Cell Mol Physiol 292: L1506-L1514, 2007. First published March 2, 2007; doi:10.1152/ajplung.00029.2007 [Abstract] [Full Text] [PDF]  

Judy L. Aschner, Susan L. Foster, Mark Kaplowitz, Yongmei Zhang, Heng Zeng, and Candice D. Fike

Heat shock protein 90 modulates endothelial nitric oxide synthase activity and vascular reactivity in the newborn piglet pulmonary circulation
Am J Physiol Lung Cell Mol Physiol 292: L1515-L1525, 2007. First published March 2, 2007; doi:10.1152/ajplung.00252.2006 [Abstract] [Full Text] [PDF]  

Pravin B. Sehgal, Somshuvra Mukhopadhyay, Fang Xu, Kirit Patel, and Mehul Shah

Dysfunction of Golgi tethers, SNAREs, and SNAPs in monocrotaline-induced pulmonary hypertension
Am J Physiol Lung Cell Mol Physiol 292: L1526-L1542, 2007. First published March 2, 2007; doi:10.1152/ajplung.00463.2006 [Abstract] [Full Text] [PDF]  

Anne Sturrock, Thomas P. Huecksteadt, Kimberly Norman, Karl Sanders, Thomas M. Murphy, Pasquale Chitano, Kimberly Wilson, John R. Hoidal, and Thomas P. Kennedy

Nox4 mediates TGF-1-induced retinoblastoma protein phosphorylation, proliferation, and hypertrophy in human airway smooth muscle cells
Am J Physiol Lung Cell Mol Physiol 292: L1543-L1555, 2007. First published March 16, 2007; doi:10.1152/ajplung.00430.2006 [Abstract] [Full Text] [PDF]  

Yuji Tada, Susan Majka, Michelle Carr, Julie Harral, Daniel Crona, Takayuki Kuriyama, and James West

Molecular effects of loss of BMPR2 signaling in smooth muscle in a transgenic mouse model of PAH
Am J Physiol Lung Cell Mol Physiol 292: L1556-L1563, 2007. First published March 16, 2007; doi:10.1152/ajplung.00305.2006 [Abstract] [Full Text] [PDF]  

Thomas Skripuletz, Andreas Schmiedl, Jutta Schade, Sammy Bedoui, Thomas Glaab, Reinhard Pabst, Stephan von Hörsten, and Michael Stephan

Dose-dependent recruitment of CD25⁺ and CD26⁺ T cells in a novel F344 rat model of asthma
Am J Physiol Lung Cell Mol Physiol 292: L1564-L1571, 2007. First published March 9, 2007; doi:10.1152/ajplung.00273.2006 [Abstract] [Full Text] [PDF]  

Kathleen A. Stringer, Meghan Tobias, Heidi C. O'Neill, and Christopher C. Franklin

Cigarette smoke extract-induced suppression of caspase-3-like activity impairs human neutrophil phagocytosis
Am J Physiol Lung Cell Mol Physiol 292: L1572-L1579, 2007. First published March 9, 2007; doi:10.1152/ajplung.00325.2006 [Abstract] [Full Text] [PDF]  

Gilman B. Allen, Timothy Leclair, Mary Cloutier, John Thompson-Figueroa, and Jason H. T. Bates

The response to recruitment worsens with progression of lung injury and fibrin accumulation in a mouse model of acid aspiration
Am J Physiol Lung Cell Mol Physiol 292: L1580-L1589, 2007. First published March 9, 2007; doi:10.1152/ajplung.00483.2006 [Abstract] [Full Text] [PDF]  

Chirag Kariya, Heather Leitner, Elysia Min, Christiaan van Heeckeren, Anna van Heeckeren, and Brian J. Day

A role for CFTR in the elevation of glutathione levels in the lung by oral glutathione administration
Am J Physiol Lung Cell Mol Physiol 292: L1590-L1597, 2007. First published March 16, 2007; doi:10.1152/ajplung.00365.2006 [Abstract] [Full Text] [PDF]  

Mo-Jun Lin, Xiao-Ru Yang, Yuan-Ning Cao, and James S. K. Sham

Hydrogen peroxide-induced Ca²⁺ mobilization in pulmonary arterial smooth muscle cells
Am J Physiol Lung Cell Mol Physiol 292: L1598-L1608, 2007. First published March 16, 2007; doi:10.1152/ajplung.00323.2006 [Abstract] [Full Text] [PDF]  

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