INVITED REVIEW:

Brigham C. Willis and Zea Borok

TGF--induced EMT: mechanisms and implications for fibrotic lung disease
Am J Physiol Lung Cell Mol Physiol 293: L525-L534, 2007. First published July 13, 2007; doi:10.1152/ajplung.00163.2007 [Abstract] [Full Text] [PDF]  

EB2007 SYMPOSIUM REPORT:

Willy Van Driessche, James L. Kreindler, Asrar B. Malik, Susan Margulies, Simon A. Lewis, and Kwang-Jin Kim

Interrelations/cross talk between transcellular transport function and paracellular tight junctional properties in lung epithelial and endothelial barriers
Am J Physiol Lung Cell Mol Physiol 293: L520-L524, 2007. First published June 29, 2007; doi:10.1152/ajplung.00218.2007 [Abstract] [Full Text] [PDF]  

EB2007 FEATURED TOPIC:

Shampa Chatterjee, Simonida Baeter, and Jahar Bhattacharya

Endothelial and epithelial signaling in the lung
Am J Physiol Lung Cell Mol Physiol 293: L517-L519, 2007. First published June 1, 2007; doi:10.1152/ajplung.00202.2007 [Abstract] [Full Text] [PDF]  

EDITORIAL FOCUS:

R. E. Olver and S. M. Wilson

Pulmonary Na⁺ transport induced by lung edema fluid
Am J Physiol Lung Cell Mol Physiol 293: L535-L536, 2007. First published June 22, 2007; doi:10.1152/ajplung.00241.2007 [Full Text] [PDF]  

Nael Elias, Bijan Rafii, Muhammad Rahman, Gail Otulakowski, Ernest Cutz, and Hugh O'Brodovich

The role of -, -, and -ENaC subunits in distal lung epithelial fluid absorption induced by pulmonary edema fluid
Am J Physiol Lung Cell Mol Physiol 293: L537-L545, 2007. First published May 18, 2007; doi:10.1152/ajplung.00373.2006 [Abstract] [Full Text] [PDF]  

Troy Stevens and Mark N. Gillespie

The hyperproliferative endothelial cell phenotype in idiopathic pulmonary arterial hypertension
Am J Physiol Lung Cell Mol Physiol 293: L546-L547, 2007. First published June 29, 2007; doi:10.1152/ajplung.00246.2007 [Full Text] [PDF]  

Fares A. Masri, Weiling Xu, Suzy A. A. Comhair, Kewal Asosingh, Michelle Koo, Amit Vasanji, Judith Drazba, Bela Anand-Apte, and Serpil C. Erzurum

Hyperproliferative apoptosis-resistant endothelial cells in idiopathic pulmonary arterial hypertension
Am J Physiol Lung Cell Mol Physiol 293: L548-L554, 2007. First published May 25, 2007; doi:10.1152/ajplung.00428.2006 [Abstract] [Full Text] [PDF]  

Tiina M. Asikainen and Carl W. White

HIF stabilizing agents: shotgun or scalpel?
Am J Physiol Lung Cell Mol Physiol 293: L555-L556, 2007. First published July 6, 2007; doi:10.1152/ajplung.00251.2007 [Full Text] [PDF]  

Freek A. Groenman, Martin Rutter, Jinxia Wang, Isabella Caniggia, Dick Tibboel, and Martin Post

Effect of chemical stabilizers of hypoxia-inducible factors on early lung development
Am J Physiol Lung Cell Mol Physiol 293: L557-L567, 2007. First published June 1, 2007; doi:10.1152/ajplung.00486.2006 [Abstract] [Full Text] [PDF]  

Donald Massaro and Gloria DeCarlo Massaro

Developmental alveologenesis: longer, differential regulation and perhaps more danger
Am J Physiol Lung Cell Mol Physiol 293: L568-L569, 2007. First published July 13, 2007; doi:10.1152/ajplung.00258.2007 [Full Text] [PDF]  

Dallas M. Hyde, Shelley A. Blozis, Mark V. Avdalovic, Lei F. Putney, Rachel Dettorre, Nathanial J. Quesenberry, Paramjit Singh, and Nancy K. Tyler

Alveoli increase in number but not size from birth to adulthood in rhesus monkeys
Am J Physiol Lung Cell Mol Physiol 293: L570-L579, 2007. First published June 22, 2007; doi:10.1152/ajplung.00467.2006 [Abstract] [Full Text] [PDF]  

Natalie R. Bauer, Timothy M. Moore, and Ivan F. McMurtry

Rodent models of PAH: are we there yet?
Am J Physiol Lung Cell Mol Physiol 293: L580-L582, 2007. First published July 27, 2007; doi:10.1152/ajplung.00281.2007 [Full Text] [PDF]  

R. James White, David F. Meoli, Robert F. Swarthout, Dara Y. Kallop, Irfan I. Galaria, Jennifer L. Harvey, Christine M. Miller, Burns C. Blaxall, Carla M. Hall, Richard A. Pierce, Carlyne D. Cool, and Mark B. Taubman

Plexiform-like lesions and increased tissue factor expression in a rat model of severe pulmonary arterial hypertension
Am J Physiol Lung Cell Mol Physiol 293: L583-L590, 2007. First published June 22, 2007; doi:10.1152/ajplung.00321.2006 [Abstract] [Full Text] [PDF] [Supplemental Video]  

ARTICLES:

Lubna H. Abdullah and C. William Davis

Regulation of airway goblet cell mucin secretion by tyrosine phosphorylation signaling pathways
Am J Physiol Lung Cell Mol Physiol 293: L591-L599, 2007. First published July 6, 2007; doi:10.1152/ajplung.00150.2007 [Abstract] [Full Text] [PDF]  

Jeffrey J. Atkinson, Holly M. Toennies, Kenn Holmbeck, and Robert M. Senior

Membrane type 1 matrix metalloproteinase is necessary for distal airway epithelial repair and keratinocyte growth factor receptor expression after acute injury
Am J Physiol Lung Cell Mol Physiol 293: L600-L610, 2007. First published June 8, 2007; doi:10.1152/ajplung.00028.2007 [Abstract] [Full Text] [PDF]  

Cherry Wongtrakool, Susanne Roser-Page, Hilda N. Rivera, and Jesse Roman

Nicotine alters lung branching morphogenesis through the ₇ nicotinic acetylcholine receptor
Am J Physiol Lung Cell Mol Physiol 293: L611-L618, 2007. First published June 1, 2007; doi:10.1152/ajplung.00038.2007 [Abstract] [Full Text] [PDF]  

Alessandra Pagano, Isabelle Métrailler-Ruchonnet, Michel Aurrand-Lions, Monica Lucattelli, Yves Donati, and Constance Barazzone Argiroffo

Poly(ADP-ribose) polymerase-1 (PARP-1) controls lung cell proliferation and repair after hyperoxia-induced lung damage
Am J Physiol Lung Cell Mol Physiol 293: L619-L629, 2007. First published June 15, 2007; doi:10.1152/ajplung.00037.2007 [Abstract] [Full Text] [PDF]  

Sven Laudi, Saskia Trump, Volker Schmitz, James West, Ivan F. McMurtry, Haitham Mutlak, Uwe Christians, Jörg Weimann, Udo Kaisers, and Wolfgang Steudel

Serotonin transporter protein in pulmonary hypertensive rats treated with atorvastatin
Am J Physiol Lung Cell Mol Physiol 293: L630-L638, 2007. First published June 15, 2007; doi:10.1152/ajplung.00110.2006 [Abstract] [Full Text] [PDF]  

M. J. Mondrinos, S. Koutzaki, P. I. Lelkes, and C. M. Finck

A tissue-engineered model of fetal distal lung tissue
Am J Physiol Lung Cell Mol Physiol 293: L639-L650, 2007. First published May 25, 2007; doi:10.1152/ajplung.00403.2006 [Abstract] [Full Text] [PDF]  

Shephali G. Gandhi, Bijan Rafii, Michael S. Harris, Alexandra Garces, Don Mahuran, Xi-Juan Chen, Hui-Fang Bao, Lucky Jain, Douglas C. Eaton, Gail Otulakowski, and Hugh O'Brodovich

Effects of cardiogenic edema fluid on ion and fluid transport in the adult lung
Am J Physiol Lung Cell Mol Physiol 293: L651-L659, 2007. First published June 8, 2007; doi:10.1152/ajplung.00464.2006 [Abstract] [Full Text] [PDF]  

Mark Salter, Keith Biggadike, Joyce L. Matthews, Michael R. West, Michael V. Haase, Stuart N. Farrow, Iain J. Uings, and David W. Gray

Pharmacological properties of the enhanced-affinity glucocorticoid fluticasone furoate in vitro and in an in vivo model of respiratory inflammatory disease
Am J Physiol Lung Cell Mol Physiol 293: L660-L667, 2007. First published June 15, 2007; doi:10.1152/ajplung.00108.2007 [Abstract] [Full Text] [PDF]  

Anser C. Azim, Hongmei Cao, Xiaopei Gao, Myungsoo Joo, Asrar B. Malik, Richard B. van Breemen, Ruxana T. Sadikot, GyeYoung Park, and John W. Christman

Regulation of cyclooxygenase-2 expression by small GTPase Rac2 in bone marrow macrophages
Am J Physiol Lung Cell Mol Physiol 293: L668-L673, 2007. First published June 15, 2007; doi:10.1152/ajplung.00043.2007 [Abstract] [Full Text] [PDF]  

Jian Wang, Letitia Weigand, Joshua Foxson, Larissa A. Shimoda, and J. T. Sylvester

Ca²⁺ signaling in hypoxic pulmonary vasoconstriction: effects of myosin light chain and Rho kinase antagonists
Am J Physiol Lung Cell Mol Physiol 293: L674-L685, 2007. First published June 15, 2007; doi:10.1152/ajplung.00141.2007 [Abstract] [Full Text] [PDF]  

Kosuke Kato, Wenju Lu, Hirofumi Kai, and K. Chul Kim

Phosphoinositide 3-kinase is activated by MUC1 but not responsible for MUC1-induced suppression of Toll-like receptor 5 signaling
Am J Physiol Lung Cell Mol Physiol 293: L686-L692, 2007. First published June 22, 2007; doi:10.1152/ajplung.00423.2006 [Abstract] [Full Text] [PDF]  

Takeshi Koga, Ippei Kuwahara, Erik P. Lillehoj, Wenju Lu, Takeshi Miyata, Yoichiro Isohama, and K. Chul Kim

TNF- induces MUC1 gene transcription in lung epithelial cells: its signaling pathway and biological implication
Am J Physiol Lung Cell Mol Physiol 293: L693-L701, 2007. First published June 15, 2007; doi:10.1152/ajplung.00491.2006 [Abstract] [Full Text] [PDF]  

Yu Gui, Gordon H. He, Michael P. Walsh, and Xi-Long Zheng

Predisposition to tetraploidy in pulmonary vascular smooth muscle cells derived from the Eker rats
Am J Physiol Lung Cell Mol Physiol 293: L702-L711, 2007. First published June 15, 2007; doi:10.1152/ajplung.00016.2007 [Abstract] [Full Text] [PDF]  

Jens F. Poschet, Graham S. Timmins, Jennifer L. Taylor-Cousar, Wojciech Ornatowski, Joseph Fazio, Elizabeth Perkett, Kari R. Wilson, Hongwei D. Yu, Hugo R. de Jonge, and Vojo Deretic

Pharmacological modulation of cGMP levels by phosphodiesterase 5 inhibitors as a therapeutic strategy for treatment of respiratory pathology in cystic fibrosis
Am J Physiol Lung Cell Mol Physiol 293: L712-L719, 2007. First published June 22, 2007; doi:10.1152/ajplung.00314.2006 [Abstract] [Full Text] [PDF] [Supplemental Figures]  

Surafel Mulugeta, Jean Ann Maguire, Jennifer L. Newitt, Scott J. Russo, Adam Kotorashvili, and Michael F. Beers

Misfolded BRICHOS SP-C mutant proteins induce apoptosis via caspase-4- and cytochrome c-related mechanisms
Am J Physiol Lung Cell Mol Physiol 293: L720-L729, 2007. First published June 22, 2007; doi:10.1152/ajplung.00025.2007 [Abstract] [Full Text] [PDF]  

Jill R. Johnson, Filip K. Swirski, Beata U. Gajewska, Ryan E. Wiley, Ramzi Fattouh, Stephanie R. Pacitto, Jonathan K. Wong, Martin R. Stämpfli, and Manel Jordana

Divergent immune responses to house dust mite lead to distinct structural-functional phenotypes
Am J Physiol Lung Cell Mol Physiol 293: L730-L739, 2007. First published June 22, 2007; doi:10.1152/ajplung.00056.2007 [Abstract] [Full Text] [PDF]  

Amy P. Wong, Andre E. Dutly, Adrian Sacher, Haeyul Lee, David M. Hwang, Mingyao Liu, Shaf Keshavjee, Jim Hu, and Thomas K. Waddell

Targeted cell replacement with bone marrow cells for airway epithelial regeneration
Am J Physiol Lung Cell Mol Physiol 293: L740-L752, 2007. First published July 6, 2007; doi:10.1152/ajplung.00050.2007 [Abstract] [Full Text] [PDF] [Supplemental Figures and Table]  

Amir Mohsenin, Tiejuan Mi, Yang Xia, Rodney E. Kellems, Jiang-Fan Chen, and Michael R. Blackburn

Genetic removal of the A_2A adenosine receptor enhances pulmonary inflammation, mucin production, and angiogenesis in adenosine deaminase-deficient mice
Am J Physiol Lung Cell Mol Physiol 293: L753-L761, 2007. First published June 29, 2007; doi:10.1152/ajplung.00187.2007 [Abstract] [Full Text] [PDF]  

Bernard M. Fischer, Shuo Zheng, Rongrong Fan, and Judith A. Voynow

Neutrophil elastase inhibition of cell cycle progression in airway epithelial cells in vitro is mediated by p27^kip1
Am J Physiol Lung Cell Mol Physiol 293: L762-L768, 2007. First published June 22, 2007; doi:10.1152/ajplung.00067.2007 [Abstract] [Full Text] [PDF]  

Leena P. Desai, Scott E. Sinclair, Kenneth E. Chapman, Aviv Hassid, and Christopher M. Waters

High tidal volume mechanical ventilation with hyperoxia alters alveolar type II cell adhesion
Am J Physiol Lung Cell Mol Physiol 293: L769-L778, 2007. First published June 29, 2007; doi:10.1152/ajplung.00127.2007 [Abstract] [Full Text] [PDF]  

Erica L. Martin, Tanya A. Sheikh, Kevin J. Leco, James F. Lewis, and Ruud A. W. Veldhuizen

Contribution of alveolar macrophages to the response of the TIMP-3 null lung during a septic insult
Am J Physiol Lung Cell Mol Physiol 293: L779-L789, 2007. First published June 22, 2007; doi:10.1152/ajplung.00442.2006 [Abstract] [Full Text] [PDF]  

Mickey M. Martin, Jessica A. Buckenberger, Jinmai Jiang, Geraldine E. Malana, Daren L. Knoell, David S. Feldman, and Terry S. Elton

TGF-1 stimulates human AT₁ receptor expression in lung fibroblasts by cross talk between the Smad, p38 MAPK, JNK, and PI3K signaling pathways
Am J Physiol Lung Cell Mol Physiol 293: L790-L799, 2007. First published June 29, 2007; doi:10.1152/ajplung.00099.2007 [Abstract] [Full Text] [PDF]  

Wendy K. Steagall, Connie G. Glasgow, Olanda M. Hathaway, Nilo A. Avila, Angelo M. Taveira-DaSilva, Antoinette Rabel, Mario P. Stylianou, Jing-Ping Lin, Xiaoling Chen, and Joel Moss

Genetic and morphologic determinants of pneumothorax in lymphangioleiomyomatosis
Am J Physiol Lung Cell Mol Physiol 293: L800-L808, 2007. First published July 6, 2007; doi:10.1152/ajplung.00176.2007 [Abstract] [Full Text] [PDF] [Supplemental Tables]  

Marilyn P. Merker, Said H. Audi, Brian J. Lindemer, Gary S. Krenz, and Robert D. Bongard

Role of mitochondrial electron transport complex I in coenzyme Q₁ reduction by intact pulmonary arterial endothelial cells and the effect of hyperoxia
Am J Physiol Lung Cell Mol Physiol 293: L809-L819, 2007. First published June 29, 2007; doi:10.1152/ajplung.00448.2006 [Abstract] [Full Text] [PDF]  

CORRIGENDA:

Corrigendum
Am J Physiol Lung Cell Mol Physiol 293: L820-L820, 2007; doi:10.1152/ajplung.zh5-5004-corr.2007 [Full Text] [PDF]  

Corrigendum
Am J Physiol Lung Cell Mol Physiol 293: L821-L821, 2007; doi:10.1152/ajplung.zh5-5005-corr.2007 [Full Text] [PDF]  

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