EDITORIAL FOCUS:

Barry Starcher

Mechanical ventilation and elastic fiber assembly
Am J Physiol Lung Cell Mol Physiol 294: L1-L2, 2008. First published October 26, 2007; doi:10.1152/ajplung.00429.2007 [Full Text] [PDF]  

Richard D. Bland, Robert Ertsey, Lucia M. Mokres, Liwen Xu, Berit E. Jacobson, Shu Jiang, Cristina M. Alvira, Marlene Rabinovitch, Eric S. Shinwell, and Anjali Dixit

Mechanical ventilation uncouples synthesis and assembly of elastin and increases apoptosis in lungs of newborn mice.: Prelude to defective alveolar septation during lung development?
Am J Physiol Lung Cell Mol Physiol 294: L3-L14, 2008. First published October 12, 2007; doi:10.1152/ajplung.00362.2007 [Abstract] [Full Text] [PDF] [Online Supplement]  

Lawrence S. Prince

Hyperoxia and EGFL7: saving cells from too much of a good thing
Am J Physiol Lung Cell Mol Physiol 294: L15-L16, 2008. First published November 9, 2007; doi:10.1152/ajplung.00455.2007 [Full Text] [PDF]  

Dong Xu, Ricardo E. Perez, Ikechukwu I. Ekekezie, Angels Navarro, and William E. Truog

Epidermal growth factor-like domain 7 protects endothelial cells from hyperoxia-induced cell death
Am J Physiol Lung Cell Mol Physiol 294: L17-L23, 2008. First published October 12, 2007; doi:10.1152/ajplung.00178.2007 [Abstract] [Full Text] [PDF]  

ARTICLES:

Anna R. Hemnes, Ari Zaiman, and Hunter C. Champion

PDE5A inhibition attenuates bleomycin-induced pulmonary fibrosis and pulmonary hypertension through inhibition of ROS generation and RhoA/Rho kinase activation
Am J Physiol Lung Cell Mol Physiol 294: L24-L33, 2008. First published October 26, 2007; doi:10.1152/ajplung.00245.2007 [Abstract] [Full Text] [PDF]  

Kamila Kitowska, Dariusz Zakrzewicz, Melanie Königshoff, Izabella Chrobak, Friedrich Grimminger, Werner Seeger, Patrick Bulau, and Oliver Eickelberg

Functional role and species-specific contribution of arginases in pulmonary fibrosis
Am J Physiol Lung Cell Mol Physiol 294: L34-L45, 2008. First published October 12, 2007; doi:10.1152/ajplung.00007.2007 [Abstract] [Full Text] [PDF]  

Shruti Sharma, Neetu Sud, Dean A. Wiseman, A. Lee Carter, Sanjiv Kumar, Yali Hou, Thomas Rau, Jason Wilham, Cynthia Harmon, Peter Oishi, Jeffrey R. Fineman, and Stephen M. Black

Altered carnitine homeostasis is associated with decreased mitochondrial function and altered nitric oxide signaling in lambs with pulmonary hypertension
Am J Physiol Lung Cell Mol Physiol 294: L46-L56, 2008. First published November 16, 2007; doi:10.1152/ajplung.00247.2007 [Abstract] [Full Text] [PDF]  

Pawan Sharma, Thai Tran, Gerald L. Stelmack, Karol McNeill, Reinoud Gosens, Mark M. Mutawe, Helmut Unruh, William T. Gerthoffer, and Andrew J. Halayko

Expression of the dystrophin-glycoprotein complex is a marker for human airway smooth muscle phenotype maturation
Am J Physiol Lung Cell Mol Physiol 294: L57-L68, 2008. First published November 9, 2007; doi:10.1152/ajplung.00378.2007 [Abstract] [Full Text] [PDF]  

Padmini Komalavilas, Raymond B. Penn, Charles R. Flynn, Jeffrey Thresher, Luciana B. Lopes, Elizabeth J. Furnish, Manhong Guo, Manuel A. Pallero, Joanne E. Murphy-Ullrich, and Colleen M. Brophy

The small heat shock-related protein, HSP20, is a cAMP-dependent protein kinase substrate that is involved in airway smooth muscle relaxation
Am J Physiol Lung Cell Mol Physiol 294: L69-L78, 2008. First published November 9, 2007; doi:10.1152/ajplung.00235.2007 [Abstract] [Full Text] [PDF]  

Alice A. Tomei, Melanie M. Choe, and Melody A. Swartz

Effects of dynamic compression on lentiviral transduction in an in vitro airway wall model
Am J Physiol Lung Cell Mol Physiol 294: L79-L86, 2008. First published November 16, 2007; doi:10.1152/ajplung.00062.2007 [Abstract] [Full Text] [PDF] [Supplemental Video]  

R. R. Mercer, J. Scabilloni, L. Wang, E. Kisin, A. R. Murray, D. Schwegler-Berry, A. A. Shvedova, and V. Castranova

Alteration of deposition pattern and pulmonary response as a result of improved dispersion of aspirated single-walled carbon nanotubes in a mouse model
Am J Physiol Lung Cell Mol Physiol 294: L87-L97, 2008. First published November 16, 2007; doi:10.1152/ajplung.00186.2007 [Abstract] [Full Text] [PDF]  

David B. Frank, Jonathan Lowery, Lynda Anderson, Monique Brink, Jeff Reese, and Mark de Caestecker

Increased susceptibility to hypoxic pulmonary hypertension in Bmpr2 mutant mice is associated with endothelial dysfunction in the pulmonary vasculature
Am J Physiol Lung Cell Mol Physiol 294: L98-L109, 2008. First published November 16, 2007; doi:10.1152/ajplung.00034.2007 [Abstract] [Full Text] [PDF] [Supplemental Figures]  

Vincent Muehlethaler, Anette M. Kunig, Gregory Seedorf, Vivek Balasubramaniam, and Steven H. Abman

Impaired VEGF and nitric oxide signaling after nitrofen exposure in rat fetal lung explants
Am J Physiol Lung Cell Mol Physiol 294: L110-L120, 2008. First published November 9, 2007; doi:10.1152/ajplung.00407.2007 [Abstract] [Full Text] [PDF]  

Anatoly N. Mikerov, Todd M. Umstead, Xiaozhuang Gan, Weixiong Huang, Xiaoxuan Guo, Guirong Wang, David S. Phelps, and Joanna Floros

Impact of ozone exposure on the phagocytic activity of human surfactant protein A (SP-A) and SP-A variants
Am J Physiol Lung Cell Mol Physiol 294: L121-L130, 2008. First published November 2, 2007; doi:10.1152/ajplung.00288.2007 [Abstract] [Full Text] [PDF]  

Karen M. Kassel, Todd A. Wyatt, Reynold A. Panettieri, Jr., and Myron L. Toews

Inhibition of human airway smooth muscle cell proliferation by β₂-adrenergic receptors and cAMP is PKA independent: evidence for EPAC involvement
Am J Physiol Lung Cell Mol Physiol 294: L131-L138, 2008. First published November 9, 2007; doi:10.1152/ajplung.00381.2007 [Abstract] [Full Text] [PDF]  

Pasquale Chitano, Lu Wang, Stanley N. Mason, Richard L. Auten, Erin N. Potts, William M. Foster, Anne Sturrock, Thomas P. Kennedy, John R. Hoidal, and Thomas M. Murphy

Airway smooth muscle relaxation is impaired in mice lacking the p47^phox subunit of NAD(P)H oxidase
Am J Physiol Lung Cell Mol Physiol 294: L139-L148, 2008. First published November 9, 2007; doi:10.1152/ajplung.00384.2007 [Abstract] [Full Text] [PDF]  

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