ANIMAL MODELS OF HUMAN LUNG DISEASE:

Joseph P. Mizgerd and Shawn J. Skerrett

Animal models of human pneumonia
Am J Physiol Lung Cell Mol Physiol 294: L387-L398, 2008. First published December 27, 2007; doi:10.1152/ajplung.00330.2007 [Abstract] [Full Text] [PDF]  

EDITORIAL FOCUS:

Hans G. Folkesson

Variations in ENaC subunit composition may determine amiloride sensitivity and β-adrenergic stimulation of lung fluid absorption
Am J Physiol Lung Cell Mol Physiol 294: L399-L400, 2008. First published January 4, 2008; doi:10.1152/ajplung.00523.2007 [Full Text] [PDF]  

Hugh O'Brodovich, Peter Yang, Shephali Gandhi, and Gail Otulakowski

Amiloride-insensitive Na⁺ and fluid absorption in the mammalian distal lung
Am J Physiol Lung Cell Mol Physiol 294: L401-L408, 2008. First published December 27, 2007; doi:10.1152/ajplung.00431.2007 [Abstract] [Full Text] [PDF]  

Nadia Randrianarison, Christine Clerici, Chrystophe Ferreira, Alexandre Fontayne, Sylvain Pradervand, Nicole Fowler-Jaeger, Edith Hummler, Bernard C. Rossier, and Carole Planès

Low expression of the β-ENaC subunit impairs lung fluid clearance in the mouse
Am J Physiol Lung Cell Mol Physiol 294: L409-L416, 2008. First published November 16, 2007; doi:10.1152/ajplung.00307.2007 [Abstract] [Full Text] [PDF]  

Jahar Bhattacharya

Lung neovascularization: a tale of two circulations
Am J Physiol Lung Cell Mol Physiol 294: L417-L418, 2008. First published January 11, 2008; doi:10.1152/ajplung.00014.2008 [Full Text] [PDF]  

Diego F. Alvarez, Lan Huang, Judy A. King, M. Khair ElZarrad, Mervin C. Yoder, and Troy Stevens

Lung microvascular endothelium is enriched with progenitor cells that exhibit vasculogenic capacity
Am J Physiol Lung Cell Mol Physiol 294: L419-L430, 2008. First published December 7, 2007; doi:10.1152/ajplung.00314.2007 [Abstract] [Full Text] [PDF]  

Jennifer Clark, Diego F. Alvarez, Mikhail Alexeyev, Judy A. C. King, Lan Huang, Mervin C. Yoder, and Troy Stevens

Regulatory role for nucleosome assembly protein-1 in the proliferative and vasculogenic phenotype of pulmonary endothelium
Am J Physiol Lung Cell Mol Physiol 294: L431-L439, 2008. First published November 2, 2007; doi:10.1152/ajplung.00316.2007 [Abstract] [Full Text] [PDF]  

Troy Stevens

Epithelium: sticking it out, together
Am J Physiol Lung Cell Mol Physiol 294: L440-L441, 2008. First published January 25, 2008; doi:10.1152/ajplung.00034.2008 [Full Text] [PDF]  

Michael C. Winter, Sandra Shasby, and D. Michael Shasby

Compromised E-cadherin adhesion and epithelial barrier function with activation of G protein-coupled receptors is rescued by Y-to-F mutations in β-catenin
Am J Physiol Lung Cell Mol Physiol 294: L442-L448, 2008. First published December 14, 2007; doi:10.1152/ajplung.00404.2007 [Abstract] [Full Text] [PDF]  

ARTICLES:

Somshuvra Mukhopadhyay, Mehul Shah, Fang Xu, Kirit Patel, Rubin M. Tuder, and Pravin B. Sehgal

Cytoplasmic provenance of STAT3 and PY-STAT3 in the endolysosomal compartments in pulmonary arterial endothelial and smooth muscle cells: implications in pulmonary arterial hypertension
Am J Physiol Lung Cell Mol Physiol 294: L449-L468, 2008. First published December 14, 2007; doi:10.1152/ajplung.00377.2007 [Abstract] [Full Text] [PDF]  

Lingxiang Zhu, Jingbo Pi, Shinichiro Wachi, Melvin E. Andersen, Reen Wu, and Yin Chen

Identification of Nrf2-dependent airway epithelial adaptive response to proinflammatory oxidant-hypochlorous acid challenge by transcription profiling
Am J Physiol Lung Cell Mol Physiol 294: L469-L477, 2008. First published December 21, 2007; doi:10.1152/ajplung.00310.2007 [Abstract] [Full Text] [PDF]  

Aruna Kode, Saravanan Rajendrasozhan, Samuel Caito, Se-Ran Yang, Ian L. Megson, and Irfan Rahman

Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke-mediated oxidative stress in human lung epithelial cells
Am J Physiol Lung Cell Mol Physiol 294: L478-L488, 2008. First published December 27, 2007; doi:10.1152/ajplung.00361.2007 [Abstract] [Full Text] [PDF]  

Jean-Marc Tadié, Priscilla Henno, Ingrid Leroy, Claire Danel, Emmanuel Naline, Christophe Faisy, Marc Riquet, Marilyne Levy, Dominique Israël-Biet, and Christophe Delclaux

Role of nitric oxide synthase/arginase balance in bronchial reactivity in patients with chronic obstructive pulmonary disease
Am J Physiol Lung Cell Mol Physiol 294: L489-L497, 2008. First published August 3, 2007; doi:10.1152/ajplung.00109.2007 [Abstract] [Full Text] [PDF]  

Jaques Belik, Darakhshanda Shehnaz, Jingyi Pan, and Hartmut Grasemann

Developmental changes in arginase expression and activity in the lung
Am J Physiol Lung Cell Mol Physiol 294: L498-L504, 2008. First published January 11, 2008; doi:10.1152/ajplung.00242.2007 [Abstract] [Full Text] [PDF]  

Lan G. Coffman, Julie C. Brown, David A. Johnson, Narayanan Parthasarathy, Ralph B. D'Agostino, Jr., Mark O. Lively, Xiaoyang Hua, Stephen L. Tilley, Werner Muller-Esterl, Mark C. Willingham, Frank M. Torti, and Suzy V. Torti

Cleavage of high-molecular-weight kininogen by elastase and tryptase is inhibited by ferritin
Am J Physiol Lung Cell Mol Physiol 294: L505-L515, 2008. First published January 11, 2008; doi:10.1152/ajplung.00347.2007 [Abstract] [Full Text] [PDF]  

Erkhembulgan Purevdorj, Katja Zscheppang, Heinz G. Hoymann, Armin Braun, Dietlinde von Mayersbach, Maria-Jantje Brinkhaus, Andreas Schmiedl, and Christiane E. L. Dammann

ErbB4 deletion leads to changes in lung function and structure similar to bronchopulmonary dysplasia
Am J Physiol Lung Cell Mol Physiol 294: L516-L522, 2008. First published January 18, 2008; doi:10.1152/ajplung.00423.2007 [Abstract] [Full Text] [PDF]  

Kentaro Mizuta, George Gallos, Defen Zhu, Fumiko Mizuta, Farida Goubaeva, Dingbang Xu, Reynold A. Panettieri, Jr., Jay Yang, and Charles W. Emala, Sr.

Expression and coupling of neurokinin receptor subtypes to inositol phosphate and calcium signaling pathways in human airway smooth muscle cells
Am J Physiol Lung Cell Mol Physiol 294: L523-L534, 2008. First published January 18, 2008; doi:10.1152/ajplung.00328.2007 [Abstract] [Full Text] [PDF]  

Guillermo M. Albaiceta, Ana Gutiérrez-Fernández, Diego Parra, Aurora Astudillo, Emilio García-Prieto, Francisco Taboada, and Antonio Fueyo

Lack of matrix metalloproteinase-9 worsens ventilator-induced lung injury
Am J Physiol Lung Cell Mol Physiol 294: L535-L543, 2008. First published January 25, 2008; doi:10.1152/ajplung.00334.2007 [Abstract] [Full Text] [PDF]  

Qihai Gu, Michelle E. Wiggers, Gerald J. Gleich, and Lu-Yuan Lee

Sensitization of isolated rat vagal pulmonary sensory neurons by eosinophil-derived cationic proteins
Am J Physiol Lung Cell Mol Physiol 294: L544-L552, 2008. First published January 4, 2008; doi:10.1152/ajplung.00271.2007 [Abstract] [Full Text] [PDF]  

H. El-Haroun, D. L. Clarke, K. Deacon, D. Bradbury, A. Clayton, A. Sutcliffe, and Alan J. Knox

IL-1β, BK, and TGF-β₁ attenuate PGI₂-mediated cAMP formation in human pulmonary artery smooth muscle cells by multiple mechanisms involving p38 MAP kinase and PKA
Am J Physiol Lung Cell Mol Physiol 294: L553-L562, 2008. First published December 21, 2007; doi:10.1152/ajplung.00044.2006 [Abstract] [Full Text] [PDF]  

Dan Ni and Lu-Yuan Lee

Effect of increasing temperature on TRPV1-mediated responses in isolated rat pulmonary sensory neurons
Am J Physiol Lung Cell Mol Physiol 294: L563-L571, 2008. First published January 4, 2008; doi:10.1152/ajplung.00336.2007 [Abstract] [Full Text] [PDF]  

Cheryl L. Fattman, Federica Gambelli, Gary Hoyle, Bruce R. Pitt, and Luis A. Ortiz

Epithelial expression of TIMP-1 does not alter sensitivity to bleomycin-induced lung injury in C57BL/6 mice
Am J Physiol Lung Cell Mol Physiol 294: L572-L581, 2008. First published January 4, 2008; doi:10.1152/ajplung.00291.2007 [Abstract] [Full Text] [PDF]  

Neetu Sud, Stephen Wedgwood, and Stephen M. Black

Protein kinase C regulates endothelial nitric oxide synthase expression via Akt activation and nitric oxide generation
Am J Physiol Lung Cell Mol Physiol 294: L582-L591, 2008. First published January 11, 2008; doi:10.1152/ajplung.00353.2007 [Abstract] [Full Text] [PDF]  

Desmond M. Murphy, Ian A. Forrest, Paul A. Corris, Gail E. Johnson, Therese Small, Debbie Jones, Andrew J. Fisher, Jim J. Egan, Timothy E. Cawston, Chris Ward, and James L. Lordan

Simvastatin attenuates release of neutrophilic and remodeling factors from primary bronchial epithelial cells derived from stable lung transplant recipients
Am J Physiol Lung Cell Mol Physiol 294: L592-L599, 2008. First published January 18, 2008; doi:10.1152/ajplung.00386.2007 [Abstract] [Full Text] [PDF]  

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