TRANSLATIONAL PHYSIOLOGY:

Martin Leustik, Stephen Doran, Andreas Bracher, Shawn Williams, Giuseppe L. Squadrito, Trenton R. Schoeb, Edward Postlethwait, and Sadis Matalon

Mitigation of chlorine-induced lung injury by low-molecular-weight antioxidants
Am J Physiol Lung Cell Mol Physiol 295: L733-L743, 2008. First published August 15, 2008; doi:10.1152/ajplung.90240.2008 [Abstract] [Full Text] [PDF]  

EDITORIAL FOCUS:

Brian Fouty

Diabetes and the pulmonary circulation
Am J Physiol Lung Cell Mol Physiol 295: L725-L726, 2008. First published September 12, 2008; doi:10.1152/ajplung.90482.2008 [Full Text] [PDF]  

Jose G. Lopez-Lopez, Javier Moral-Sanz, Giovanna Frazziano, Maria J. Gomez-Villalobos, Jorge Flores-Hernandez, Eduardo Monjaraz, Angel Cogolludo, and Francisco Perez-Vizcaino

Diabetes induces pulmonary artery endothelial dysfunction by NADPH oxidase induction
Am J Physiol Lung Cell Mol Physiol 295: L727-L732, 2008. First published August 22, 2008; doi:10.1152/ajplung.90354.2008 [Abstract] [Full Text] [PDF]  

ARTICLES:

James West, Julie Harral, Kirk Lane, Yupu Deng, Brian Ickes, Daniel Crona, Sebastian Albu, Duncan Stewart, and Karen Fagan

Mice expressing BMPR2^R899X transgene in smooth muscle develop pulmonary vascular lesions
Am J Physiol Lung Cell Mol Physiol 295: L744-L755, 2008. First published August 22, 2008; doi:10.1152/ajplung.90255.2008 [Abstract] [Full Text] [PDF] [Supplemental Figures and Tables]  

Peter E. Oishi, Dean A. Wiseman, Shruti Sharma, Sanjiv Kumar, Yali Hou, Sanjeev A. Datar, Anthony Azakie, Michael J. Johengen, Cynthia Harmon, Sohrab Fratz, Jeffrey R. Fineman, and Stephen M. Black

Progressive dysfunction of nitric oxide synthase in a lamb model of chronically increased pulmonary blood flow: a role for oxidative stress
Am J Physiol Lung Cell Mol Physiol 295: L756-L766, 2008. First published August 29, 2008; doi:10.1152/ajplung.00146.2007 [Abstract] [Full Text] [PDF]  

Nicholas W. Lukacs, Aaron A. Berlin, Karin Franz-Bacon, Roman Sásik, L. James Sprague, Tai Wei Ly, Gary Hardiman, Stefen A. Boehme, and Kevin B. Bacon

CRTH2 antagonism significantly ameliorates airway hyperreactivity and downregulates inflammation-induced genes in a mouse model of airway inflammation
Am J Physiol Lung Cell Mol Physiol 295: L767-L779, 2008. First published August 29, 2008; doi:10.1152/ajplung.90351.2008 [Abstract] [Full Text] [PDF]  

Jill R. Johnson, Stephanie R. Pacitto, Jonathan Wong, Elliot W. Archer, Stefan Eirefelt, Anna Miller-Larsson, and Manel Jordana

Combined budesonide/formoterol therapy in conjunction with allergen avoidance ameliorates house dust mite-induced airway remodeling and dysfunction
Am J Physiol Lung Cell Mol Physiol 295: L780-L788, 2008. First published September 5, 2008; doi:10.1152/ajplung.90229.2008 [Abstract] [Full Text] [PDF]  

Metin Aytekin, Suzy A. A. Comhair, Carol de la Motte, Sudip K. Bandyopadhyay, Carol F. Farver, Vincent C. Hascall, Serpil C. Erzurum, and Raed A. Dweik

High levels of hyaluronan in idiopathic pulmonary arterial hypertension
Am J Physiol Lung Cell Mol Physiol 295: L789-L799, 2008. First published September 5, 2008; doi:10.1152/ajplung.90306.2008 [Abstract] [Full Text] [PDF]  

Tomohiro Ichikawa, Hisatoshi Sugiura, Akira Koarai, Satoru Yanagisawa, Masae Kanda, Atsushi Hayata, Kanako Furukawa, Keiichiro Akamatsu, Tsunahiko Hirano, Masanori Nakanishi, Kazuto Matsunaga, Yoshiaki Minakata, and Masakazu Ichinose

Peroxynitrite augments fibroblast-mediated tissue remodeling via myofibroblast differentiation
Am J Physiol Lung Cell Mol Physiol 295: L800-L808, 2008. First published September 12, 2008; doi:10.1152/ajplung.90264.2008 [Abstract] [Full Text] [PDF] [Supplemental Figures]  

Mary E. Manson, Deborah A. Corey, Nicole M. White, and Thomas J. Kelley

cAMP-mediated regulation of cholesterol accumulation in cystic fibrosis and Niemann-Pick type C cells
Am J Physiol Lung Cell Mol Physiol 295: L809-L819, 2008. First published September 12, 2008; doi:10.1152/ajplung.90402.2008 [Abstract] [Full Text] [PDF]  

Paula R. Pedreira, Emilio García-Prieto, Diego Parra, Aurora Astudillo, Elena Diaz, Francisco Taboada, and Guillermo M. Albaiceta

Effects of melatonin in an experimental model of ventilator-induced lung injury
Am J Physiol Lung Cell Mol Physiol 295: L820-L827, 2008. First published September 19, 2008; doi:10.1152/ajplung.90211.2008 [Abstract] [Full Text] [PDF]  

Adeleke M. Badejo, Jr., Jasdeep S. Dhaliwal, David B. Casey, Thomas B. Gallen, Anthony J. Greco, and Philip J. Kadowitz

Analysis of pulmonary vasodilator responses to the Rho-kinase inhibitor fasudil in the anesthetized rat
Am J Physiol Lung Cell Mol Physiol 295: L828-L836, 2008. First published August 8, 2008; doi:10.1152/ajplung.00042.2008 [Abstract] [Full Text] [PDF]  

A. P. Albert, A. M. Woollhead, O. J. Mace, and D. L. Baines

AICAR decreases the activity of two distinct amiloride-sensitive Na⁺-permeable channels in H441 human lung epithelial cell monolayers
Am J Physiol Lung Cell Mol Physiol 295: L837-L848, 2008. First published August 22, 2008; doi:10.1152/ajplung.90353.2008 [Abstract] [Full Text] [PDF]  

Edward Felder, Marcus Siebenbrunner, Tobias Busch, Giorgio Fois, Pika Miklavc, Paul Walther, and Paul Dietl

Mechanical strain of alveolar type II cells in culture: changes in the transcellular cytokeratin network and adaptations
Am J Physiol Lung Cell Mol Physiol 295: L849-L857, 2008. First published August 15, 2008; doi:10.1152/ajplung.00503.2007 [Abstract] [Full Text] [PDF]  

Kevin Kwong, Marian Kollarik, Christina Nassenstein, Fei Ru, and Bradley J. Undem

P2X2 receptors differentiate placodal vs. neural crest C-fiber phenotypes innervating guinea pig lungs and esophagus
Am J Physiol Lung Cell Mol Physiol 295: L858-L865, 2008. First published August 8, 2008; doi:10.1152/ajplung.90360.2008 [Abstract] [Full Text] [PDF]  

Nguyen Thu Ngan Trinh, Anik Privé, Emilie Maillé, Josette Noël, and Emmanuelle Brochiero

EGF and K⁺ channel activity control normal and cystic fibrosis bronchial epithelia repair
Am J Physiol Lung Cell Mol Physiol 295: L866-L880, 2008. First published August 29, 2008; doi:10.1152/ajplung.90224.2008 [Abstract] [Full Text] [PDF]  

Candice D. Fike, James C. Slaughter, Mark R. Kaplowitz, Yongmei Zhang, and Judy L. Aschner

Reactive oxygen species from NADPH oxidase contribute to altered pulmonary vascular responses in piglets with chronic hypoxia-induced pulmonary hypertension
Am J Physiol Lung Cell Mol Physiol 295: L881-L888, 2008. First published August 29, 2008; doi:10.1152/ajplung.00047.2008 [Abstract] [Full Text] [PDF]  

Yuansheng Gao, Ada D. Portugal, Jie Liu, Sewite Negash, Weilin Zhou, Jia Tian, Ruolan Xiang, Lawrence D. Longo, and J. Usha Raj

Preservation of cGMP-induced relaxation of pulmonary veins of fetal lambs exposed to chronic high altitude hypoxia: role of PKG and Rho kinase
Am J Physiol Lung Cell Mol Physiol 295: L889-L896, 2008. First published August 29, 2008; doi:10.1152/ajplung.00463.2007 [Abstract] [Full Text] [PDF]  

Dan Ni and Lu-Yuan Lee

Lack of potentiating effect of increasing temperature on responses to chemical activators in vagal sensory neurons isolated from TRPV1-null mice
Am J Physiol Lung Cell Mol Physiol 295: L897-L904, 2008. First published August 29, 2008; doi:10.1152/ajplung.90385.2008 [Abstract] [Full Text] [PDF]  

Ravi Goyal, Kara D. Creel, Erica Chavis, Gregory D. Smith, Lawrence D. Longo, and Sean M. Wilson

Maturation of intracellular calcium homeostasis in sheep pulmonary arterial smooth muscle cells
Am J Physiol Lung Cell Mol Physiol 295: L905-L914, 2008. First published September 5, 2008; doi:10.1152/ajplung.00053.2008 [Abstract] [Full Text] [PDF]  

Dinesh K. Hirenallur-S., Steven T. Haworth, Jeaninne T. Leming, James Chang, Guillermo Hernandez, John B. Gordon, and Nancy J. Rusch

Upregulation of vascular calcium channels in neonatal piglets with hypoxia-induced pulmonary hypertension
Am J Physiol Lung Cell Mol Physiol 295: L915-L924, 2008. First published September 5, 2008; doi:10.1152/ajplung.90286.2008 [Abstract] [Full Text] [PDF]  

Prerna Rastogi, Dawn M. Young, and Jane McHowat

Tryptase activates calcium-independent phospholipase A₂ and releases PGE₂ in airway epithelial cells
Am J Physiol Lung Cell Mol Physiol 295: L925-L932, 2008. First published September 12, 2008; doi:10.1152/ajplung.90230.2008 [Abstract] [Full Text] [PDF]  

Kelvin D. MacDonald, Karen R. McKenzie, Mark J. Henderson, Charles E. Hawkins, Neeraj Vij, and Pamela L. Zeitlin

Lubiprostone activates non-CFTR-dependent respiratory epithelial chloride secretion in cystic fibrosis mice
Am J Physiol Lung Cell Mol Physiol 295: L933-L940, 2008. First published September 19, 2008; doi:10.1152/ajplung.90221.2008 [Abstract] [Full Text] [PDF]  

Aigul Moldobaeva, John Jenkins, and Elizabeth Wagner

Effects of distension on airway inflammation and venular P-selectin expression
Am J Physiol Lung Cell Mol Physiol 295: L941-L948, 2008. First published September 19, 2008; doi:10.1152/ajplung.90447.2008 [Abstract] [Full Text] [PDF]  

Christopher J. Delvecchio, Patricia Bilan, Parameswaran Nair, and John P. Capone

LXR-induced reverse cholesterol transport in human airway smooth muscle is mediated exclusively by ABCA1
Am J Physiol Lung Cell Mol Physiol 295: L949-L957, 2008. First published September 26, 2008; doi:10.1152/ajplung.90394.2008 [Abstract] [Full Text] [PDF]  

Leena P. Desai, Kenneth E. Chapman, and Christopher M. Waters

Mechanical stretch decreases migration of alveolar epithelial cells through mechanisms involving Rac1 and Tiam1
Am J Physiol Lung Cell Mol Physiol 295: L958-L965, 2008. First published September 19, 2008; doi:10.1152/ajplung.90218.2008 [Abstract] [Full Text] [PDF]  

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