AJP - Lung Cellular and Molecular Physiology -- Table of Contents (November 1 2009, 297 [5])

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TRANSLATIONAL PHYSIOLOGY:

David P. Nichols, Assem G. Ziady, Samuel L. Shank, Jean F. Eastman, and Pamela B. Davis: The triterpenoid CDDO limits inflammation in preclinical models of cystic fibrosis lung disease
Am J Physiol Lung Cell Mol Physiol 297: L828-L836, 2009. First published August 21, 2009; doi:10.1152/ajplung.00171.2009 [Abstract] [Full Text] [PDF] [Supplemental Figures]

EDITORIAL FOCUS:

Paul J. Wolters: Could N-acetylcysteine slow progression of idiopathic pulmonary fibrosis by inhibiting EMT?
Am J Physiol Lung Cell Mol Physiol 297: L803-L804, 2009. First published August 21, 2009; doi:10.1152/ajplung.00283.2009 [Full Text] [PDF]

V. M. Felton, Z. Borok, and B. C. Willis: N-acetylcysteine inhibits alveolar epithelial-mesenchymal transition
Am J Physiol Lung Cell Mol Physiol 297: L805-L812, 2009. First published July 31, 2009; doi:10.1152/ajplung.00009.2009 [Abstract] [Full Text] [PDF]

David H. Ingbar, Maneesh Bhargava, and Scott M. O'Grady: Mechanisms of alveolar epithelial chloride absorption
Am J Physiol Lung Cell Mol Physiol 297: L813-L815, 2009. First published September 25, 2009; doi:10.1152/ajplung.00324.2009 [Full Text] [PDF]

Meshell Johnson, Lennell Allen, and Leland Dobbs: Characteristics of Cl^– uptake in rat alveolar type I cells
Am J Physiol Lung Cell Mol Physiol 297: L816-L827, 2009. First published August 14, 2009; doi:10.1152/ajplung.90466.2008 [Abstract] [Full Text] [PDF]

ARTICLES:

Uwe Pfeil, Muhammad Aslam, Renate Paddenberg, Karin Quanz, Chia L. Chang, Jae-Il Park, Barbara Gries, Amir Rafiq, Petra Faulhammer, Anna Goldenberg, Tamara Papadakis, Thomas Noll, Sheau Y. T. Hsu, Norbert Weissmann, and Wolfgang Kummer: Intermedin/adrenomedullin-2 is a hypoxia-induced endothelial peptide that stabilizes pulmonary microvascular permeability
Am J Physiol Lung Cell Mol Physiol 297: L837-L845, 2009. First published August 14, 2009; doi:10.1152/ajplung.90608.2008 [Abstract] [Full Text] [PDF]

Shubha Murthy, Andrea Adamcakova-Dodd, Sarah S. Perry, Linda A. Tephly, Richard M. Keller, Nervana Metwali, David K. Meyerholz, Yongqiang Wang, Michael Glogauer, Peter S. Thorne, and A. Brent Carter: Modulation of reactive oxygen species by Rac1 or catalase prevents asbestos-induced pulmonary fibrosis
Am J Physiol Lung Cell Mol Physiol 297: L846-L855, 2009. First published August 14, 2009; doi:10.1152/ajplung.90590.2008 [Abstract] [Full Text] [PDF]

Melissa A. Cercone, William Schroeder, Stacey Schomberg, and Todd C. Carpenter: EphA2 receptor mediates increased vascular permeability in lung injury due to viral infection and hypoxia
Am J Physiol Lung Cell Mol Physiol 297: L856-L863, 2009. First published August 14, 2009; doi:10.1152/ajplung.00118.2009 [Abstract] [Full Text] [PDF]

Weichao Guo, Bin Shan, Ross C. Klingsberg, Xiangmei Qin, and Joseph A. Lasky: Abrogation of TGF-β1-induced fibroblast-myofibroblast differentiation by histone deacetylase inhibition
Am J Physiol Lung Cell Mol Physiol 297: L864-L870, 2009. First published August 21, 2009; doi:10.1152/ajplung.00128.2009 [Abstract] [Full Text] [PDF] [Supplemental Figures]

Elena M. Sorokina, Sheldon I. Feinstein, Tatyana N. Milovanova, and Aron B. Fisher: Identification of the amino acid sequence that targets peroxiredoxin 6 to lysosome-like structures of lung epithelial cells
Am J Physiol Lung Cell Mol Physiol 297: L871-L880, 2009. First published August 21, 2009; doi:10.1152/ajplung.00052.2009 [Abstract] [Full Text] [PDF]

H. C. Yalcin, K. M. Hallow, J. Wang, M. T. Wei, H. D. Ou-Yang, and S. N. Ghadiali: Influence of cytoskeletal structure and mechanics on epithelial cell injury during cyclic airway reopening
Am J Physiol Lung Cell Mol Physiol 297: L881-L891, 2009. First published August 21, 2009; doi:10.1152/ajplung.90562.2008 [Abstract] [Full Text] [PDF]

Chuen-Mao Yang, I-Ta Lee, Chih-Chung Lin, Ya-Lin Yang, Shue-Fen Luo, Yu Ru Kou, and Li-Der Hsiao: Cigarette smoke extract induces COX-2 expression via a PKC ${alpha}$ /c-Src/EGFR, PDGFR/PI3K/Akt/NF- ${kappa}$ B pathway and p300 in tracheal smooth muscle cells
Am J Physiol Lung Cell Mol Physiol 297: L892-L902, 2009. First published August 28, 2009; doi:10.1152/ajplung.00151.2009 [Abstract] [Full Text] [PDF] [Supplemental Figures]

Jorina Geys, Rita De Vos, Benoit Nemery, and Peter H. M. Hoet: In vitro translocation of quantum dots and influence of oxidative stress
Am J Physiol Lung Cell Mol Physiol 297: L903-L911, 2009. First published September 4, 2009; doi:10.1152/ajplung.00029.2009 [Abstract] [Full Text] [PDF]

Heather E. Ferguson, Thomas H. Thatcher, Keith C. Olsen, Tatiana M. Garcia-Bates, Carolyn J. Baglole, R. M. Kottmann, Emily R. Strong, Richard P. Phipps, and Patricia J. Sime: Peroxisome proliferator-activated receptor- ${gamma}$ ligands induce heme oxygenase-1 in lung fibroblasts by a PPAR ${gamma}$ -independent, glutathione-dependent mechanism
Am J Physiol Lung Cell Mol Physiol 297: L912-L919, 2009. First published September 4, 2009; doi:10.1152/ajplung.00148.2009 [Abstract] [Full Text] [PDF]

Azhar Masood, Man Yi, Mandy Lau, Rosetta Belcastro, Samuel Shek, Jingyi Pan, Crystal Kantores, Patrick J. McNamara, Brian P. Kavanagh, Jaques Belik, Robert P. Jankov, and A. Keith Tanswell: Therapeutic effects of hypercapnia on chronic lung injury and vascular remodeling in neonatal rats
Am J Physiol Lung Cell Mol Physiol 297: L920-L930, 2009. First published September 11, 2009; doi:10.1152/ajplung.00139.2009 [Abstract] [Full Text] [PDF]

Umadevi Sajjan, Shyamala Ganesan, Adam T. Comstock, Jee Shim, Qiong Wang, Deepti R. Nagarkar, Ying Zhao, Adam M. Goldsmith, Joanne Sonstein, Marisa J. Linn, Jeffrey L. Curtis, and Marc B. Hershenson: Elastase- and LPS-exposed mice display altered responses to rhinovirus infection
Am J Physiol Lung Cell Mol Physiol 297: L931-L944, 2009. First published September 11, 2009; doi:10.1152/ajplung.00150.2009 [Abstract] [Full Text] [PDF] [Supplemental Figures]

Meng Zhang, Ling Lin, Seon-Jin Lee, Li Mo, Jiaofei Cao, Emeka Ifedigbo, and Yang Jin: Deletion of caveolin-1 protects hyperoxia-induced apoptosis via survivin-mediated pathways
Am J Physiol Lung Cell Mol Physiol 297: L945-L953, 2009. First published September 18, 2009; doi:10.1152/ajplung.00081.2009 [Abstract] [Full Text] [PDF]

Heather N. Woodward, Adil Anwar, Suzette Riddle, Laimute Taraseviciene-Stewart, Miguel Fragoso, Kurt R. Stenmark, and Evgenia V. Gerasimovskaya: PI3K, Rho, and ROCK play a key role in hypoxia-induced ATP release and ATP-stimulated angiogenic responses in pulmonary artery vasa vasorum endothelial cells
Am J Physiol Lung Cell Mol Physiol 297: L954-L964, 2009. First published August 14, 2009; doi:10.1152/ajplung.00038.2009 [Abstract] [Full Text] [PDF] [Supplemental Figures]

Marie-Laure Franco-Montoya, Jacques R. Bourbon, Xavier Durrmeyer, Stéphanie Lorotte, Pierre-Henri Jarreau, and Christophe Delacourt: Pulmonary effects of keratinocyte growth factor in newborn rats exposed to hyperoxia
Am J Physiol Lung Cell Mol Physiol 297: L965-L976, 2009. First published August 21, 2009; doi:10.1152/ajplung.00136.2009 [Abstract] [Full Text] [PDF]

Farzaneh Ketabchi, Bakytbek Egemnazarov, Ralph T. Schermuly, Hossein A. Ghofrani, Werner Seeger, Friedrich Grimminger, Mostafa Shid-Moosavi, Gholam A. Dehghani, Norbert Weissmann, and Natascha Sommer: Effects of hypercapnia with and without acidosis on hypoxic pulmonary vasoconstriction
Am J Physiol Lung Cell Mol Physiol 297: L977-L983, 2009. First published August 28, 2009; doi:10.1152/ajplung.00074.2009 [Abstract] [Full Text] [PDF]

Yoshihiko Chiba, Shunsuke Sato, Motohiko Hanazaki, Hiroyasu Sakai, and Miwa Misawa: Inhibition of geranylgeranyltransferase inhibits bronchial smooth muscle hyperresponsiveness in mice
Am J Physiol Lung Cell Mol Physiol 297: L984-L991, 2009. First published August 28, 2009; doi:10.1152/ajplung.00178.2009 [Abstract] [Full Text] [PDF]

Megan O'Reilly, Stuart B. Hooper, Beth J. Allison, Sharon J. Flecknoe, Ken Snibson, Richard Harding, and Foula Sozo: Persistent bronchiolar remodeling following brief ventilation of the very immature ovine lung
Am J Physiol Lung Cell Mol Physiol 297: L992-L1001, 2009. First published August 28, 2009; doi:10.1152/ajplung.00099.2009 [Abstract] [Full Text] [PDF]

Keith D. Salazar, Susan M. Lankford, and Arnold R. Brody: Mesenchymal stem cells produce Wnt isoforms and TGF-β₁ that mediate proliferation and procollagen expression by lung fibroblasts
Am J Physiol Lung Cell Mol Physiol 297: L1002-L1011, 2009. First published September 4, 2009; doi:10.1152/ajplung.90347.2008 [Abstract] [Full Text] [PDF]

REVIEW:

D. W. Reid, G. J. Anderson, and I. L. Lamont: Role of lung iron in determining the bacterial and host struggle in cystic fibrosis
Am J Physiol Lung Cell Mol Physiol 297: L795-L802, 2009. First published August 21, 2009; doi:10.1152/ajplung.00132.2009 [Abstract] [Full Text] [PDF]

Cover Caption:

Cover

Cover: Colocalization of α₅-integrin with u-PAR in lamellipodia of spreading human lung fibroblasts. Fibroblasts were attached to fibronectin-coated glass coverslips for 15–30 min in attachment assay buffer. The cells were fixed and then immunostained for u-PAR (green) and for α₅-integrins (red). Photomicrographs were performed (original magnification, ×1000), and the basal 1-μm Z-stack images were selected and merged. Yellow color indicates colocalization. Lamellipodia are the peripheral protrusive structures. From Am J Physiol Lung Cell Mol Physiol 297: L97–L108, 2009.